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	<title>Genetik (Methoden) - Versionsgeschichte</title>
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		<title>Ossip Groth am 10. April 2010 um 18:34 Uhr</title>
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		<updated>2010-04-10T18:34:21Z</updated>

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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Nächstältere Version&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Version vom 10. April 2010, 18:34 Uhr&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l5&quot;&gt;Zeile 5:&lt;/td&gt;
&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot;&gt;Zeile 5:&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|-&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;|-&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| bgcolor=&amp;quot;#dfdfdf&amp;quot; | &amp;#039;&amp;#039;&amp;#039;Freie Übersichtsartikel&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| bgcolor=&amp;quot;#dfdfdf&amp;quot; | &amp;#039;&amp;#039;&amp;#039;Freie Übersichtsartikel&amp;#039;&amp;#039;&amp;#039;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;−&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| align=&quot;left&quot; width=&quot;800&quot; |&amp;lt;ref name=&quot;PMID18394581&quot;&amp;gt;Bayesian meta-analysis of genetic association studies with different sets of markers. Am J Hum Genet 82(4):859-72 (2008) PMID 18394581 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18304491&quot;&amp;gt;Robust score statistics for QTL linkage analysis. Am J Hum Genet 82(3):567-82 (2008) PMID 18304491 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18252216&quot;&amp;gt;A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet 82(2):352-65 (2008) PMID 18252216 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17668371&quot;&amp;gt;New perspectives for the elucidation of genetic disorders. Am J Hum Genet 81(2):199-207 (2007) PMID 17668371 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17160891&quot;&amp;gt;Genome scanning by composite likelihood. Am J Hum Genet 80(1):19-28 (2007) PMID 17160891 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16380906&quot;&amp;gt;Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. Am J Hum Genet 77(6):937-44 (2005) PMID 16380906 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16080110&quot;&amp;gt;Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet 77(3):337-45 (2005) PMID 16080110 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15786018&quot;&amp;gt;Nonparametric tests of association of multiple genes with human disease. Am J Hum Genet 76(5):780-93 (2005) PMID 15786018 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15311375&quot;&amp;gt;Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. Am J Hum Genet 75(4):687-92 (2004) PMID 15311375 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15272419&quot;&amp;gt;The future of association studies: gene-based analysis and replication. Am J Hum Genet 75(3):353-62 (2004) PMID 15272419 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID14574645&quot;&amp;gt;A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73(5):1162-9 (2003) PMID 14574645 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12802787&quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis. Am J Hum Genet 73(1):17-33 (2003) PMID 12802787 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12802786&quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet 73(1):34-48 (2003) PMID 12802786 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12802785&quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet 73(1):49-62 (2003) PMID 12802785 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12772086&quot;&amp;gt;Hot and cold spots of recombination in the human genome: the reason we should find them and how this can be achieved. Am J Hum Genet 73(1):5-16 (2003) PMID 12772086 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12037716&quot;&amp;gt;Meta-analysis of genetic-linkage analysis of quantitative-trait loci. Am J Hum Genet 71(1):56-65 (2002) PMID 12037716 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID11791212&quot;&amp;gt;Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70(2):425-34 (2002) PMID 11791212 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID11565063&quot;&amp;gt;Genomewide scans of complex human diseases: true linkage is hard to find. Am J Hum Genet 69(5):936-50 (2001) PMID 11565063 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID10884361&quot;&amp;gt;Statistical approaches to gene mapping. Am J Hum Genet 67(2):289-94 (2000) PMID 10884361 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID9973303&quot;&amp;gt;Power of association and linkage tests when the disease alleles are unobserved. Am J Hum Genet 64(2):641-9 (1999) PMID 9973303 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID7992829&quot;&amp;gt;Comparative genomic hybridization: an overview. Am J Pathol 145(6):1253-60 (1994) PMID 7992829 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18505780&quot;&amp;gt;Whole genome scanning as a cytogenetic tool in hematologic malignancies. Blood 112(4):965-74 (2008) PMID 18505780 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16451653&quot;&amp;gt;Identifying genomic regions for fine-mapping using genome scan meta-analysis (GSMA) to identify the minimum regions of maximum significance (MRMS) across populations. BMC Genet 6 Suppl 1():S42 (2005) PMID 16451653 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12021160&quot;&amp;gt;Perspective: how to make microarray, serial analysis of gene expression, and proteomic relevant to day-to-day endocrine problems and physiological systems. Endocrinology 143(6):1995-2001 (2002) PMID 12021160 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18523451&quot;&amp;gt;Identification of human haploinsufficient genes and their genomic proximity to segmental duplications. Eur J Hum Genet 16(11):1350-7 (2008) PMID 18523451 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18523454&quot;&amp;gt;Gene-environment interactions for complex traits: definitions, methodological requirements and challenges. Eur J Hum Genet 16(10):1164-72 (2008) PMID 18523454 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18285837&quot;&amp;gt;The success of the genome-wide association approach: a brief story of a long struggle. Eur J Hum Genet 16(5):554-64 (2008) PMID 18285837 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17637806&quot;&amp;gt;Guidelines for molecular karyotyping in constitutional genetic diagnosis. Eur J Hum Genet 15(11):1105-14 (2007) PMID 17637806 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17377519&quot;&amp;gt;Meta-analysis of genome-wide linkage studies for multiple sclerosis, using an extended GSMA method. Eur J Hum Genet 15(6):703-10 (2007) PMID 17377519 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16288307&quot;&amp;gt;Recent advances in array comparative genomic hybridization technologies and their applications in human genetics. Eur J Hum Genet 14(2):139-48 (2006) PMID 16288307 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID9801865&quot;&amp;gt;Parallel molecular genetic analysis. Eur J Hum Genet 6(5):417-29 (1998) PMID 9801865 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID9781018&quot;&amp;gt;Modifier genes in humans: strategies for identification. Eur J Hum Genet 6(1):80-8 (1998) PMID 9781018 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18852205&quot;&amp;gt;Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet 17(R2):R156-65 (2008) PMID 18852205 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18852196&quot;&amp;gt;Genome-wide association studies: past, present and future. Hum Mol Genet 17(R2):R100-1 (2008) PMID 18852196 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18451988&quot;&amp;gt;A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118(5):1590-605 (2008) PMID 18451988 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15931376&quot;&amp;gt;Mapping quantitative trait loci in humans: achievements and limitations. J Clin Invest 115(6):1419-24 (2005) PMID 15931376 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15931375&quot;&amp;gt;Factors affecting statistical power in the detection of genetic association. J Clin Invest 115(6):1408-18 (2005) PMID 15931375 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17142807&quot;&amp;gt;Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Multi-organ whole-genome measurements and reverse engineering to uncover gene networks underlying complex traits. J Lipid Res 48(2):267-77 (2007) PMID 17142807 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID6086927&quot;&amp;gt;Blot hybridisation analysis of genomic DNA. J Med Genet 21(3):164-72 (1984) PMID 6086927 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12839081&quot;&amp;gt;Primer on medical genomics. Part VIII: Essentials of medical genetics for the practicing physician. Mayo Clin Proc 78(7):846-57 (2003) PMID 12839081 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12744545&quot;&amp;gt;Primer on medical genomics. Part VII: The evolving concept of the gene. Mayo Clin Proc 78(5):580-7 (2003) PMID 12744545 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12630584&quot;&amp;gt;Primer on medical genomics. Part VI: Genomics and molecular genetics in clinical practice. Mayo Clin Proc 78(3):307-17 (2003) PMID 12630584 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12528878&quot;&amp;gt;Primer on medical genomics part V: bioinformatics. Mayo Clin Proc 78(1):57-64 (2003) PMID 12528878 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12173714&quot;&amp;gt;Primer on medical genomics part II: Background principles and methods in molecular genetics. Mayo Clin Proc 77(8):785-808 (2002) PMID 12173714 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID10748872&quot;&amp;gt;Comparative genomic hybridisation. Mol Pathol 52(5):243-51 (1999) PMID 10748872 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID19916168&quot;&amp;gt;Genome-wide association studies--a summary for the clinical gastroenterologist. World J Gastroenterol 15(43):5377-96 (2009) PMID 19916168 &amp;lt;/ref&amp;gt;&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;| align=&quot;left&quot; width=&quot;800&quot; |&amp;lt;ref name=&quot;PMID18394581&quot;&amp;gt;Bayesian meta-analysis of genetic association studies with different sets of markers. Am J Hum Genet 82(4):859-72 (2008) PMID 18394581 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18304491&quot;&amp;gt;Robust score statistics for QTL linkage analysis. Am J Hum Genet 82(3):567-82 (2008) PMID 18304491 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18252216&quot;&amp;gt;A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet 82(2):352-65 (2008) PMID 18252216 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17668371&quot;&amp;gt;New perspectives for the elucidation of genetic disorders. Am J Hum Genet 81(2):199-207 (2007) PMID 17668371 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17160891&quot;&amp;gt;Genome scanning by composite likelihood. Am J Hum Genet 80(1):19-28 (2007) PMID 17160891 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16380906&quot;&amp;gt;Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. Am J Hum Genet 77(6):937-44 (2005) PMID 16380906 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16080110&quot;&amp;gt;Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet 77(3):337-45 (2005) PMID 16080110 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15786018&quot;&amp;gt;Nonparametric tests of association of multiple genes with human disease. Am J Hum Genet 76(5):780-93 (2005) PMID 15786018 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15311375&quot;&amp;gt;Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. Am J Hum Genet 75(4):687-92 (2004) PMID 15311375 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15272419&quot;&amp;gt;The future of association studies: gene-based analysis and replication. Am J Hum Genet 75(3):353-62 (2004) PMID 15272419 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID14574645&quot;&amp;gt;A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73(5):1162-9 (2003) PMID 14574645 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12802787&quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis. Am J Hum Genet 73(1):17-33 (2003) PMID 12802787 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12802786&quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet 73(1):34-48 (2003) PMID 12802786 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12802785&quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet 73(1):49-62 (2003) PMID 12802785 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12772086&quot;&amp;gt;Hot and cold spots of recombination in the human genome: the reason we should find them and how this can be achieved. Am J Hum Genet 73(1):5-16 (2003) PMID 12772086 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12037716&quot;&amp;gt;Meta-analysis of genetic-linkage analysis of quantitative-trait loci. Am J Hum Genet 71(1):56-65 (2002) PMID 12037716 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID11791212&quot;&amp;gt;Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70(2):425-34 (2002) PMID 11791212 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID11565063&quot;&amp;gt;Genomewide scans of complex human diseases: true linkage is hard to find. Am J Hum Genet 69(5):936-50 (2001) PMID 11565063 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID10884361&quot;&amp;gt;Statistical approaches to gene mapping. Am J Hum Genet 67(2):289-94 (2000) PMID 10884361 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID9973303&quot;&amp;gt;Power of association and linkage tests when the disease alleles are unobserved. Am J Hum Genet 64(2):641-9 (1999) PMID 9973303 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID7992829&quot;&amp;gt;Comparative genomic hybridization: an overview. Am J Pathol 145(6):1253-60 (1994) PMID 7992829 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18505780&quot;&amp;gt;Whole genome scanning as a cytogenetic tool in hematologic malignancies. Blood 112(4):965-74 (2008) PMID 18505780 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16451653&quot;&amp;gt;Identifying genomic regions for fine-mapping using genome scan meta-analysis (GSMA) to identify the minimum regions of maximum significance (MRMS) across populations. BMC Genet 6 Suppl 1():S42 (2005) PMID 16451653 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12021160&quot;&amp;gt;Perspective: how to make microarray, serial analysis of gene expression, and proteomic relevant to day-to-day endocrine problems and physiological systems. Endocrinology 143(6):1995-2001 (2002) PMID 12021160 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18523451&quot;&amp;gt;Identification of human haploinsufficient genes and their genomic proximity to segmental duplications. Eur J Hum Genet 16(11):1350-7 (2008) PMID 18523451 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18523454&quot;&amp;gt;Gene-environment interactions for complex traits: definitions, methodological requirements and challenges. Eur J Hum Genet 16(10):1164-72 (2008) PMID 18523454 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18285837&quot;&amp;gt;The success of the genome-wide association approach: a brief story of a long struggle. Eur J Hum Genet 16(5):554-64 (2008) PMID 18285837 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17637806&quot;&amp;gt;Guidelines for molecular karyotyping in constitutional genetic diagnosis. Eur J Hum Genet 15(11):1105-14 (2007) PMID 17637806 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17377519&quot;&amp;gt;Meta-analysis of genome-wide linkage studies for multiple sclerosis, using an extended GSMA method. Eur J Hum Genet 15(6):703-10 (2007) PMID 17377519 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID16288307&quot;&amp;gt;Recent advances in array comparative genomic hybridization technologies and their applications in human genetics. Eur J Hum Genet 14(2):139-48 (2006) PMID 16288307 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID9801865&quot;&amp;gt;Parallel molecular genetic analysis. Eur J Hum Genet 6(5):417-29 (1998) PMID 9801865 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID9781018&quot;&amp;gt;Modifier genes in humans: strategies for identification. Eur J Hum Genet 6(1):80-8 (1998) PMID 9781018 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18852205&quot;&amp;gt;Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet 17(R2):R156-65 (2008) PMID 18852205 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18852196&quot;&amp;gt;Genome-wide association studies: past, present and future. Hum Mol Genet 17(R2):R100-1 (2008) PMID 18852196 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID18451988&quot;&amp;gt;A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118(5):1590-605 (2008) PMID 18451988 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15931376&quot;&amp;gt;Mapping quantitative trait loci in humans: achievements and limitations. J Clin Invest 115(6):1419-24 (2005) PMID 15931376 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID15931375&quot;&amp;gt;Factors affecting statistical power in the detection of genetic association. J Clin Invest 115(6):1408-18 (2005) PMID 15931375 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID17142807&quot;&amp;gt;Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Multi-organ whole-genome measurements and reverse engineering to uncover gene networks underlying complex traits. J Lipid Res 48(2):267-77 (2007) PMID 17142807 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID6086927&quot;&amp;gt;Blot hybridisation analysis of genomic DNA. J Med Genet 21(3):164-72 (1984) PMID 6086927 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12839081&quot;&amp;gt;Primer on medical genomics. Part VIII: Essentials of medical genetics for the practicing physician. Mayo Clin Proc 78(7):846-57 (2003) PMID 12839081 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12744545&quot;&amp;gt;Primer on medical genomics. Part VII: The evolving concept of the gene. Mayo Clin Proc 78(5):580-7 (2003) PMID 12744545 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12630584&quot;&amp;gt;Primer on medical genomics. Part VI: Genomics and molecular genetics in clinical practice. Mayo Clin Proc 78(3):307-17 (2003) PMID 12630584 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12528878&quot;&amp;gt;Primer on medical genomics part V: bioinformatics. Mayo Clin Proc 78(1):57-64 (2003) PMID 12528878 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID12173714&quot;&amp;gt;Primer on medical genomics part II: Background principles and methods in molecular genetics. Mayo Clin Proc 77(8):785-808 (2002) PMID 12173714 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID10748872&quot;&amp;gt;Comparative genomic hybridisation. Mol Pathol 52(5):243-51 (1999) PMID 10748872 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID19916168&quot;&amp;gt;Genome-wide association studies--a summary for the clinical gastroenterologist. World J Gastroenterol 15(43):5377-96 (2009) PMID 19916168 &amp;lt;/ref&amp;gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;ref name=&quot;PMID16049310&quot;&amp;gt;Genotyping microarray for the detection of more than 200 CFTR mutations in ethnically diverse populations. J Mol Diagn 7(3):375-87 (2005) PMID 16049310 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&quot;PMID11950952&quot;&amp;gt;Methods of molecular analysis: mutation detection in solid tumours. Mol Pathol 55(2):73-9 (2002) PMID 11950952 &amp;lt;/ref&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt; &lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
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&lt;/table&gt;</summary>
		<author><name>Ossip Groth</name></author>
	</entry>
	<entry>
		<id>https://ddn.pluspedia.org/w/index.php?title=Genetik_(Methoden)&amp;diff=39395&amp;oldid=prev</id>
		<title>Ossip Groth: Die Seite wurde neu angelegt: „Entstehender Artikel {| class=&quot;wikitable&quot; | | bgcolor=&quot;#dfdfdf&quot; | &#039;&#039;&#039;Siehe auch&#039;&#039;&#039; | align=&quot;left&quot; width=&quot;800&quot; | |- | bgcolor=&quot;#d…“</title>
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		<updated>2010-03-28T18:49:10Z</updated>

		<summary type="html">&lt;p&gt;Die Seite wurde neu angelegt: „&lt;a href=&quot;/wiki/Datei:Pptpdtjpg1.png&quot; title=&quot;Datei:Pptpdtjpg1.png&quot;&gt;miniatur|Entstehender Artikel&lt;/a&gt; {| class=&amp;quot;wikitable&amp;quot; | | bgcolor=&amp;quot;#dfdfdf&amp;quot; | &amp;#039;&amp;#039;&amp;#039;Siehe auch&amp;#039;&amp;#039;&amp;#039; | align=&amp;quot;left&amp;quot; width=&amp;quot;800&amp;quot; | |- | bgcolor=&amp;quot;#d…“&lt;/p&gt;
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| align=&amp;quot;left&amp;quot; width=&amp;quot;800&amp;quot; |&amp;lt;ref name=&amp;quot;PMID18394581&amp;quot;&amp;gt;Bayesian meta-analysis of genetic association studies with different sets of markers. Am J Hum Genet 82(4):859-72 (2008) PMID 18394581 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18304491&amp;quot;&amp;gt;Robust score statistics for QTL linkage analysis. Am J Hum Genet 82(3):567-82 (2008) PMID 18304491 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18252216&amp;quot;&amp;gt;A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet 82(2):352-65 (2008) PMID 18252216 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID17668371&amp;quot;&amp;gt;New perspectives for the elucidation of genetic disorders. Am J Hum Genet 81(2):199-207 (2007) PMID 17668371 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID17160891&amp;quot;&amp;gt;Genome scanning by composite likelihood. Am J Hum Genet 80(1):19-28 (2007) PMID 17160891 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID16380906&amp;quot;&amp;gt;Genomewide high-density SNP linkage analysis of 236 Japanese families supports the existence of schizophrenia susceptibility loci on chromosomes 1p, 14q, and 20p. Am J Hum Genet 77(6):937-44 (2005) PMID 16380906 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID16080110&amp;quot;&amp;gt;Recent developments in genomewide association scans: a workshop summary and review. Am J Hum Genet 77(3):337-45 (2005) PMID 16080110 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID15786018&amp;quot;&amp;gt;Nonparametric tests of association of multiple genes with human disease. Am J Hum Genet 76(5):780-93 (2005) PMID 15786018 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID15311375&amp;quot;&amp;gt;Guidelines for genotyping in genomewide linkage studies: single-nucleotide-polymorphism maps versus microsatellite maps. Am J Hum Genet 75(4):687-92 (2004) PMID 15311375 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID15272419&amp;quot;&amp;gt;The future of association studies: gene-based analysis and replication. Am J Hum Genet 75(3):353-62 (2004) PMID 15272419 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID14574645&amp;quot;&amp;gt;A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 73(5):1162-9 (2003) PMID 14574645 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12802787&amp;quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part I: Methods and power analysis. Am J Hum Genet 73(1):17-33 (2003) PMID 12802787 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12802786&amp;quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet 73(1):34-48 (2003) PMID 12802786 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12802785&amp;quot;&amp;gt;Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet 73(1):49-62 (2003) PMID 12802785 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12772086&amp;quot;&amp;gt;Hot and cold spots of recombination in the human genome: the reason we should find them and how this can be achieved. Am J Hum Genet 73(1):5-16 (2003) PMID 12772086 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12037716&amp;quot;&amp;gt;Meta-analysis of genetic-linkage analysis of quantitative-trait loci. Am J Hum Genet 71(1):56-65 (2002) PMID 12037716 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID11791212&amp;quot;&amp;gt;Score tests for association between traits and haplotypes when linkage phase is ambiguous. Am J Hum Genet 70(2):425-34 (2002) PMID 11791212 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID11565063&amp;quot;&amp;gt;Genomewide scans of complex human diseases: true linkage is hard to find. Am J Hum Genet 69(5):936-50 (2001) PMID 11565063 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID10884361&amp;quot;&amp;gt;Statistical approaches to gene mapping. Am J Hum Genet 67(2):289-94 (2000) PMID 10884361 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID9973303&amp;quot;&amp;gt;Power of association and linkage tests when the disease alleles are unobserved. Am J Hum Genet 64(2):641-9 (1999) PMID 9973303 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID7992829&amp;quot;&amp;gt;Comparative genomic hybridization: an overview. Am J Pathol 145(6):1253-60 (1994) PMID 7992829 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18505780&amp;quot;&amp;gt;Whole genome scanning as a cytogenetic tool in hematologic malignancies. Blood 112(4):965-74 (2008) PMID 18505780 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID16451653&amp;quot;&amp;gt;Identifying genomic regions for fine-mapping using genome scan meta-analysis (GSMA) to identify the minimum regions of maximum significance (MRMS) across populations. BMC Genet 6 Suppl 1():S42 (2005) PMID 16451653 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12021160&amp;quot;&amp;gt;Perspective: how to make microarray, serial analysis of gene expression, and proteomic relevant to day-to-day endocrine problems and physiological systems. Endocrinology 143(6):1995-2001 (2002) PMID 12021160 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18523451&amp;quot;&amp;gt;Identification of human haploinsufficient genes and their genomic proximity to segmental duplications. Eur J Hum Genet 16(11):1350-7 (2008) PMID 18523451 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18523454&amp;quot;&amp;gt;Gene-environment interactions for complex traits: definitions, methodological requirements and challenges. Eur J Hum Genet 16(10):1164-72 (2008) PMID 18523454 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18285837&amp;quot;&amp;gt;The success of the genome-wide association approach: a brief story of a long struggle. Eur J Hum Genet 16(5):554-64 (2008) PMID 18285837 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID17637806&amp;quot;&amp;gt;Guidelines for molecular karyotyping in constitutional genetic diagnosis. Eur J Hum Genet 15(11):1105-14 (2007) PMID 17637806 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID17377519&amp;quot;&amp;gt;Meta-analysis of genome-wide linkage studies for multiple sclerosis, using an extended GSMA method. Eur J Hum Genet 15(6):703-10 (2007) PMID 17377519 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID16288307&amp;quot;&amp;gt;Recent advances in array comparative genomic hybridization technologies and their applications in human genetics. Eur J Hum Genet 14(2):139-48 (2006) PMID 16288307 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID9801865&amp;quot;&amp;gt;Parallel molecular genetic analysis. Eur J Hum Genet 6(5):417-29 (1998) PMID 9801865 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID9781018&amp;quot;&amp;gt;Modifier genes in humans: strategies for identification. Eur J Hum Genet 6(1):80-8 (1998) PMID 9781018 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18852205&amp;quot;&amp;gt;Genome-wide association studies: potential next steps on a genetic journey. Hum Mol Genet 17(R2):R156-65 (2008) PMID 18852205 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18852196&amp;quot;&amp;gt;Genome-wide association studies: past, present and future. Hum Mol Genet 17(R2):R100-1 (2008) PMID 18852196 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID18451988&amp;quot;&amp;gt;A HapMap harvest of insights into the genetics of common disease. J Clin Invest 118(5):1590-605 (2008) PMID 18451988 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID15931376&amp;quot;&amp;gt;Mapping quantitative trait loci in humans: achievements and limitations. J Clin Invest 115(6):1419-24 (2005) PMID 15931376 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID15931375&amp;quot;&amp;gt;Factors affecting statistical power in the detection of genetic association. J Clin Invest 115(6):1408-18 (2005) PMID 15931375 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID17142807&amp;quot;&amp;gt;Thematic review series: systems biology approaches to metabolic and cardiovascular disorders. Multi-organ whole-genome measurements and reverse engineering to uncover gene networks underlying complex traits. J Lipid Res 48(2):267-77 (2007) PMID 17142807 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID6086927&amp;quot;&amp;gt;Blot hybridisation analysis of genomic DNA. J Med Genet 21(3):164-72 (1984) PMID 6086927 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12839081&amp;quot;&amp;gt;Primer on medical genomics. Part VIII: Essentials of medical genetics for the practicing physician. Mayo Clin Proc 78(7):846-57 (2003) PMID 12839081 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12744545&amp;quot;&amp;gt;Primer on medical genomics. Part VII: The evolving concept of the gene. Mayo Clin Proc 78(5):580-7 (2003) PMID 12744545 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12630584&amp;quot;&amp;gt;Primer on medical genomics. Part VI: Genomics and molecular genetics in clinical practice. Mayo Clin Proc 78(3):307-17 (2003) PMID 12630584 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12528878&amp;quot;&amp;gt;Primer on medical genomics part V: bioinformatics. Mayo Clin Proc 78(1):57-64 (2003) PMID 12528878 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID12173714&amp;quot;&amp;gt;Primer on medical genomics part II: Background principles and methods in molecular genetics. Mayo Clin Proc 77(8):785-808 (2002) PMID 12173714 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID10748872&amp;quot;&amp;gt;Comparative genomic hybridisation. Mol Pathol 52(5):243-51 (1999) PMID 10748872 &amp;lt;/ref&amp;gt;&amp;lt;ref name=&amp;quot;PMID19916168&amp;quot;&amp;gt;Genome-wide association studies--a summary for the clinical gastroenterologist. World J Gastroenterol 15(43):5377-96 (2009) PMID 19916168 &amp;lt;/ref&amp;gt;&lt;br /&gt;
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----&lt;br /&gt;
&lt;br /&gt;
== Bibliographie ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
&lt;br /&gt;
{{LinkWP_Miniartikel|Txt=Genetik (Methoden)|Link=Genetik}}&lt;/div&gt;</summary>
		<author><name>Ossip Groth</name></author>
	</entry>
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