Prion - Versionsgeschichte

Fmrauch: Text und Krankheiten dazu

2025-12-07T17:19:22Z

Text und Krankheiten dazu

← Nächstältere Version		Version vom 7. Dezember 2025, 17:19 Uhr
Zeile 1:		Zeile 1:
	'''Prionen''' sind [[Protein]]e, die im tierischen Organismus sowohl in ~~[[physiologisch]]en~~ (normalen) als auch in [[pathogen]]en (gesundheitsschädigenden) [[Konformation]]en (Strukturen) vorliegen können. Sie vermehren sich nicht durch Teilung, sondern durch induzierte Veränderung benachbarter Moleküle.<ref name="PMID18391177">Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref><ref name="PMID18245809">Prion diseases: from protein to cell pathology. Am J Pathol 172(3):555-65 (2008) PMID 18245809 </ref><ref name="PMID7717447">Etiology and pathogenesis of prion diseases. Am J Pathol 146(4):785-811 (1995) PMID 7717447 </ref><ref name="PMID4626566">Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. Am J Pathol 68(3):626-52 (1972) PMID 4626566 </ref><ref name="PMID16606761">Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63(4):497-501 (2006) PMID 16606761 </ref><ref name="PMID15824251">Human prion diseases: molecular and clinical aspects. Arch Neurol 62(4):545-52 (2005) PMID 15824251 </ref><ref name="PMID10190828">Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 56(3):357-62 (1999) PMID 10190828 </ref><ref name="PMID15154834">Prions in control of cell glycosylation. Biochem J 380(Pt 2):e5-6 (2004) PMID 15154834 </ref><ref name="PMID1968741">Prion liposomes. Biochem J 266(1):1-14 (1990) PMID 1968741 </ref><ref name="PMID16923955">Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 129(Pt 9):2297-317 (2006) PMID 16923955 </ref><ref name="PMID16816391">A systematic review of prion therapeutics in experimental models. Brain 129(Pt 9):2241-65 (2006) PMID 16816391 </ref><ref name="PMID10581227">How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 122 ( Pt 12)():2345-51 (1999) PMID 10581227 </ref><ref name="PMID11279534">Pathogenesis of prion diseases: a progress report. Cell Death Differ 7(10):889-902 (2000) PMID 11279534 </ref><ref name="PMID16391566">Prion disease genetics. Eur J Hum Genet 14(3):273-81 (2006) PMID 16391566 </ref><ref name="PMID11788778">A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. Exp Biol Med (Maywood) 227(1):4-19 (2002) PMID 11788778 </ref><ref name="PMID11444100">Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. Exp Biol Med (Maywood) 226(7):640-52 (2001) PMID 11444100 </ref><ref name="PMID11444099">A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to "new variant" CJD and bovine spongiform encephalopathy. Exp Biol Med (Maywood) 226(7):629-39 (2001) PMID 11444099 </ref><ref name="PMID19618341">Transmissible mink encephalopathy - review of the etiology of a rare prion disease. Folia Neuropathol 47(2):195-204 (2009) PMID 19618341 </ref><ref name="PMID19618336">Cannibalism, kuru and anthropology. Folia Neuropathol 47(2):138-44 (2009) PMID 19618336 </ref><ref name="PMID19618335">Kuru and D. Carleton Gajdusek: a close encounter. Folia Neuropathol 47(2):114-37 (2009) PMID 19618335 </ref><ref name="PMID19618334">Thoughts on mammalian prion strains. Folia Neuropathol 47(2):104-13 (2009) PMID 19618334 </ref><ref name="PMID19618333">Reflections on a half-century in the field of transmissible spongiform encephalopathy. Folia Neuropathol 47(2):95-103 (2009) PMID 19618333 </ref><ref name="PMID18587704">Prion diseases: a riddle wrapped in a mystery inside an enigma. Folia Neuropathol 46(2):93-116 (2008) PMID 18587704 </ref><ref name="PMID18368623">Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). Folia Neuropathol 46(1):1-25 (2008) PMID 18368623 </ref><ref name="PMID16823692">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 2. Folia Neuropathol 44(2):102-10 (2006) PMID 16823692 </ref><ref name="PMID16823691">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 1. Folia Neuropathol 44(2):93-101 (2006) PMID 16823691 </ref><ref name="PMID16416388">Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. Folia Neuropathol 43(4):229-43 (2005) PMID 16416388 </ref><ref name="PMID15037545">Prions: proteins as genes and infectious entities. Genes Dev 18(5):470-85 (2004) PMID 15037545 </ref><ref name="PMID16420684">Unraveling prion structures and biological functions. Genome Biol 6(13):366 (2005) PMID 16420684 </ref><ref name="PMID15820951">Prions and the blood and immune systems. Haematologica 90(4):542-8 (2005) PMID 15820951 </ref><ref name="PMID9300662">Human prion diseases and bovine spongiform encephalopathy (BSE). Hum Mol Genet 6(10):1699-705 (1997) PMID 9300662 </ref><ref name="PMID7642588">Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem 270(33):19197-200 (1995) PMID 7642588 </ref><ref name="PMID828205">Scrapie: a review of its relation to human disease and ageing. J Med Genet 13(6):479-95 (1976) PMID 828205 </ref><ref name="PMID15965195">Molecular neurology of prion disease. J Neurol Neurosurg Psychiatry 76(7):906-19 (2005) PMID 15965195 </ref><ref name="PMID14978149">Prion diseases. J Neurol Neurosurg Psychiatry 75 Suppl 1():i36-42 (2004) PMID 14978149 </ref><ref name="PMID1955893">The spongiform encephalopathies. J Neurol Neurosurg Psychiatry 54(9):761-3 (1991) PMID 1955893 </ref><ref name="PMID11724914">The molecular pathology of CJD: old and new variants. Mol Pathol 54(6):393-9 (2001) PMID 11724914 </ref><ref name="PMID9373595">Creutzfeldt-Jakob disease in the elderly. Postgrad Med J 73(863):557-9 (1997) PMID 9373595 </ref><ref name="PMID223140">Slow viruses and chronic disease of the central nervous system. Postgrad Med J 55(640):143-9 (1979) PMID 223140 </ref><ref name="PMID103082">Creutzfeldt--Jakob disease. Postgrad Med J 54(635):591-4 (1978) PMID 103082 </ref><ref name="PMID19242120">Prions in the environment: occurrence, fate and mitigation. Prion 2(4):162-9 (2008) PMID 19242120 </ref><ref name="PMID19172115">An emerging concept of prion infections as a form of transmissible cerebral amyloidosis. Prion 1(4):223-7 (2007) PMID 19172115 </ref><ref name="PMID19172114">Biological roles of prion domains. Prion 1(4):228-35 (2007) PMID 19172114 </ref><ref name="PMID19164911">A structural overview of the vertebrate prion proteins. Prion 1(3):185-97 (2007) PMID 19164911 </ref><ref name="PMID19164897">Prion stability. Prion 1(3):170-8 (2007) PMID 19164897 </ref><ref name="PMID19164893">Prion-prion interactions. Prion 1(3):161-9 (2007) PMID 19164893 </ref><ref name="PMID19164928">Yeast prions: evolution of the prion concept. Prion 1(2):94-100 (2007) PMID 19164928 </ref><ref name="PMID19164891">Prions and related phenomena. Prion 1(2):81-2 (2007) PMID 19164891 </ref><ref name="PMID19164923">Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. Prion 1(1):48-52 (2007) PMID 19164923 </ref><ref name="PMID9811807">Prions. Proc Natl Acad Sci U S A 95(23):13363-83 (1998) PMID 9811807 </ref><ref name="PMID8197105">Inherited prion diseases. Proc Natl Acad Sci U S A 91(11):4611-4 (1994) PMID 8197105 </ref><ref name="PMID7975565">Neurodegeneration in humans caused by prions. West J Med 161(3):264-72 (1994) PMID 7975565 </ref><ref name="PMID3284206">Creutzfeldt-Jakob disease, 1988. West J Med 148(3):328-9 (1988) PMID 3284206 </ref><ref name="PMID14744440">Mammalian prion biology: one century of evolving concepts. Cell 116(2):313-27 (2004) PMID 14744440 </ref><ref name="PMID9590169">Prion protein biology. Cell 93(3):337-48 (1998) PMID 9590169 </ref><ref name="PMID10801430">Prions: Portable prion domains. Curr Biol 10(9):R335-7 (2000) PMID 10801430 </ref><ref name="PMID11832240">The utility of prions. Dev Cell 2(2):143-51 (2002) PMID 11832240 </ref><ref name="PMID12354606">Prion diseases: pathogenesis and public health concerns. FEBS Lett 529(1):17-21 (2002) PMID 12354606 </ref><ref name="PMID11852045">Cellular prion protein: on the road for functions. FEBS Lett 512(1-3):25-8 (2002) PMID 11852045 </ref><ref name="PMID8682199">The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies. FEBS Lett 389(1):3-11 (1996) PMID 8682199 </ref><ref name="PMID10545332">Prion protein interconversions and the transmissible spongiform encephalopathies. Structure 7(10):R231-40 (1999) PMID 10545332 </ref>		'''Prionen''' sind [[Protein]]e, die im tierischen Organismus sowohl in physiologischen (normalen) als auch in [[pathogen]]en (gesundheitsschädigenden) [[Konformation]]en (Strukturen) vorliegen können. Sie vermehren und verbreiten sich nicht durch Teilung, sondern durch induzierte Veränderung benachbarter Moleküle.<ref name="PMID18391177">Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref><ref name="PMID18245809">Prion diseases: from protein to cell pathology. Am J Pathol 172(3):555-65 (2008) PMID 18245809 </ref><ref name="PMID7717447">Etiology and pathogenesis of prion diseases. Am J Pathol 146(4):785-811 (1995) PMID 7717447 </ref> Die pathogenen Prionen sind mit großer Wahrscheinlichkeit für die [[Creutzfeldt-Jakob-Krankheit]] beim Menschen, [[Bovine spongiforme Enzephalopathie\|BSE]] („Rinderwahn“) beim [[Hausrind\|Rind]] oder [[Scrapie]] („Traberkrankheit“) bei [[Hausschaf\|Schafen]] verantwortlich.<ref name="PMID4626566">Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. Am J Pathol 68(3):626-52 (1972) PMID 4626566 </ref><ref name="PMID16606761">Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63(4):497-501 (2006) PMID 16606761 </ref><ref name="PMID15824251">Human prion diseases: molecular and clinical aspects. Arch Neurol 62(4):545-52 (2005) PMID 15824251 </ref><ref name="PMID10190828">Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 56(3):357-62 (1999) PMID 10190828 </ref><ref name="PMID15154834">Prions in control of cell glycosylation. Biochem J 380(Pt 2):e5-6 (2004) PMID 15154834 </ref><ref name="PMID1968741">Prion liposomes. Biochem J 266(1):1-14 (1990) PMID 1968741 </ref><ref name="PMID16923955">Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 129(Pt 9):2297-317 (2006) PMID 16923955 </ref><ref name="PMID16816391">A systematic review of prion therapeutics in experimental models. Brain 129(Pt 9):2241-65 (2006) PMID 16816391 </ref><ref name="PMID10581227">How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 122 ( Pt 12)():2345-51 (1999) PMID 10581227 </ref><ref name="PMID11279534">Pathogenesis of prion diseases: a progress report. Cell Death Differ 7(10):889-902 (2000) PMID 11279534 </ref><ref name="PMID16391566">Prion disease genetics. Eur J Hum Genet 14(3):273-81 (2006) PMID 16391566 </ref><ref name="PMID11788778">A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. Exp Biol Med (Maywood) 227(1):4-19 (2002) PMID 11788778 </ref><ref name="PMID11444100">Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. Exp Biol Med (Maywood) 226(7):640-52 (2001) PMID 11444100 </ref><ref name="PMID11444099">A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to "new variant" CJD and bovine spongiform encephalopathy. Exp Biol Med (Maywood) 226(7):629-39 (2001) PMID 11444099 </ref><ref name="PMID19618341">Transmissible mink encephalopathy - review of the etiology of a rare prion disease. Folia Neuropathol 47(2):195-204 (2009) PMID 19618341 </ref><ref name="PMID19618336">Cannibalism, kuru and anthropology. Folia Neuropathol 47(2):138-44 (2009) PMID 19618336 </ref><ref name="PMID19618335">Kuru and D. Carleton Gajdusek: a close encounter. Folia Neuropathol 47(2):114-37 (2009) PMID 19618335 </ref><ref name="PMID19618334">Thoughts on mammalian prion strains. Folia Neuropathol 47(2):104-13 (2009) PMID 19618334 </ref><ref name="PMID19618333">Reflections on a half-century in the field of transmissible spongiform encephalopathy. Folia Neuropathol 47(2):95-103 (2009) PMID 19618333 </ref><ref name="PMID18587704">Prion diseases: a riddle wrapped in a mystery inside an enigma. Folia Neuropathol 46(2):93-116 (2008) PMID 18587704 </ref><ref name="PMID18368623">Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). Folia Neuropathol 46(1):1-25 (2008) PMID 18368623 </ref><ref name="PMID16823692">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 2. Folia Neuropathol 44(2):102-10 (2006) PMID 16823692 </ref><ref name="PMID16823691">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 1. Folia Neuropathol 44(2):93-101 (2006) PMID 16823691 </ref><ref name="PMID16416388">Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. Folia Neuropathol 43(4):229-43 (2005) PMID 16416388 </ref><ref name="PMID15037545">Prions: proteins as genes and infectious entities. Genes Dev 18(5):470-85 (2004) PMID 15037545 </ref><ref name="PMID16420684">Unraveling prion structures and biological functions. Genome Biol 6(13):366 (2005) PMID 16420684 </ref><ref name="PMID15820951">Prions and the blood and immune systems. Haematologica 90(4):542-8 (2005) PMID 15820951 </ref><ref name="PMID9300662">Human prion diseases and bovine spongiform encephalopathy (BSE). Hum Mol Genet 6(10):1699-705 (1997) PMID 9300662 </ref><ref name="PMID7642588">Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem 270(33):19197-200 (1995) PMID 7642588 </ref><ref name="PMID828205">Scrapie: a review of its relation to human disease and ageing. J Med Genet 13(6):479-95 (1976) PMID 828205 </ref><ref name="PMID15965195">Molecular neurology of prion disease. J Neurol Neurosurg Psychiatry 76(7):906-19 (2005) PMID 15965195 </ref><ref name="PMID14978149">Prion diseases. J Neurol Neurosurg Psychiatry 75 Suppl 1():i36-42 (2004) PMID 14978149 </ref><ref name="PMID1955893">The spongiform encephalopathies. J Neurol Neurosurg Psychiatry 54(9):761-3 (1991) PMID 1955893 </ref><ref name="PMID11724914">The molecular pathology of CJD: old and new variants. Mol Pathol 54(6):393-9 (2001) PMID 11724914 </ref><ref name="PMID9373595">Creutzfeldt-Jakob disease in the elderly. Postgrad Med J 73(863):557-9 (1997) PMID 9373595 </ref><ref name="PMID223140">Slow viruses and chronic disease of the central nervous system. Postgrad Med J 55(640):143-9 (1979) PMID 223140 </ref><ref name="PMID103082">Creutzfeldt--Jakob disease. Postgrad Med J 54(635):591-4 (1978) PMID 103082 </ref><ref name="PMID19242120">Prions in the environment: occurrence, fate and mitigation. Prion 2(4):162-9 (2008) PMID 19242120 </ref><ref name="PMID19172115">An emerging concept of prion infections as a form of transmissible cerebral amyloidosis. Prion 1(4):223-7 (2007) PMID 19172115 </ref><ref name="PMID19172114">Biological roles of prion domains. Prion 1(4):228-35 (2007) PMID 19172114 </ref><ref name="PMID19164911">A structural overview of the vertebrate prion proteins. Prion 1(3):185-97 (2007) PMID 19164911 </ref><ref name="PMID19164897">Prion stability. Prion 1(3):170-8 (2007) PMID 19164897 </ref><ref name="PMID19164893">Prion-prion interactions. Prion 1(3):161-9 (2007) PMID 19164893 </ref><ref name="PMID19164928">Yeast prions: evolution of the prion concept. Prion 1(2):94-100 (2007) PMID 19164928 </ref><ref name="PMID19164891">Prions and related phenomena. Prion 1(2):81-2 (2007) PMID 19164891 </ref><ref name="PMID19164923">Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. Prion 1(1):48-52 (2007) PMID 19164923 </ref><ref name="PMID9811807">Prions. Proc Natl Acad Sci U S A 95(23):13363-83 (1998) PMID 9811807 </ref><ref name="PMID8197105">Inherited prion diseases. Proc Natl Acad Sci U S A 91(11):4611-4 (1994) PMID 8197105 </ref><ref name="PMID7975565">Neurodegeneration in humans caused by prions. West J Med 161(3):264-72 (1994) PMID 7975565 </ref><ref name="PMID3284206">Creutzfeldt-Jakob disease, 1988. West J Med 148(3):328-9 (1988) PMID 3284206 </ref><ref name="PMID14744440">Mammalian prion biology: one century of evolving concepts. Cell 116(2):313-27 (2004) PMID 14744440 </ref><ref name="PMID9590169">Prion protein biology. Cell 93(3):337-48 (1998) PMID 9590169 </ref><ref name="PMID10801430">Prions: Portable prion domains. Curr Biol 10(9):R335-7 (2000) PMID 10801430 </ref><ref name="PMID11832240">The utility of prions. Dev Cell 2(2):143-51 (2002) PMID 11832240 </ref><ref name="PMID12354606">Prion diseases: pathogenesis and public health concerns. FEBS Lett 529(1):17-21 (2002) PMID 12354606 </ref><ref name="PMID11852045">Cellular prion protein: on the road for functions. FEBS Lett 512(1-3):25-8 (2002) PMID 11852045 </ref><ref name="PMID8682199">The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies. FEBS Lett 389(1):3-11 (1996) PMID 8682199 </ref><ref name="PMID10545332">Prion protein interconversions and the transmissible spongiform encephalopathies. Structure 7(10):R231-40 (1999) PMID 10545332 </ref>

	== Bibliographie ==		== Bibliographie ==

Fmrauch am 7. Dezember 2025 um 17:15 Uhr

2025-12-07T17:15:24Z

@@ Zeile 1: / Zeile 1: @@
-[[Datei:pptpdtjpg1.png|miniatur|Entstehender Artikel]]
+'''Prionen''' sind [[Protein]]e, die im tierischen Organismus sowohl in [[physiologisch]]en (normalen) als auch in [[pathogen]]en (gesundheitsschädigenden) [[Konformation]]en (Strukturen) vorliegen können. Sie vermehren sich nicht durch Teilung, sondern durch induzierte Veränderung benachbarter Moleküle.<ref name="PMID18391177">Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref><ref name="PMID18245809">Prion diseases: from protein to cell pathology. Am J Pathol 172(3):555-65 (2008) PMID 18245809 </ref><ref name="PMID7717447">Etiology and pathogenesis of prion diseases. Am J Pathol 146(4):785-811 (1995) PMID 7717447 </ref><ref name="PMID4626566">Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. Am J Pathol 68(3):626-52 (1972) PMID 4626566 </ref><ref name="PMID16606761">Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63(4):497-501 (2006) PMID 16606761 </ref><ref name="PMID15824251">Human prion diseases: molecular and clinical aspects. Arch Neurol 62(4):545-52 (2005) PMID 15824251 </ref><ref name="PMID10190828">Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 56(3):357-62 (1999) PMID 10190828 </ref><ref name="PMID15154834">Prions in control of cell glycosylation. Biochem J 380(Pt 2):e5-6 (2004) PMID 15154834 </ref><ref name="PMID1968741">Prion liposomes. Biochem J 266(1):1-14 (1990) PMID 1968741 </ref><ref name="PMID16923955">Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 129(Pt 9):2297-317 (2006) PMID 16923955 </ref><ref name="PMID16816391">A systematic review of prion therapeutics in experimental models. Brain 129(Pt 9):2241-65 (2006) PMID 16816391 </ref><ref name="PMID10581227">How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 122 ( Pt 12)():2345-51 (1999) PMID 10581227 </ref><ref name="PMID11279534">Pathogenesis of prion diseases: a progress report. Cell Death Differ 7(10):889-902 (2000) PMID 11279534 </ref><ref name="PMID16391566">Prion disease genetics. Eur J Hum Genet 14(3):273-81 (2006) PMID 16391566 </ref><ref name="PMID11788778">A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. Exp Biol Med (Maywood) 227(1):4-19 (2002) PMID 11788778 </ref><ref name="PMID11444100">Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. Exp Biol Med (Maywood) 226(7):640-52 (2001) PMID 11444100 </ref><ref name="PMID11444099">A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to &quot;new variant&quot; CJD and bovine spongiform encephalopathy. Exp Biol Med (Maywood) 226(7):629-39 (2001) PMID 11444099 </ref><ref name="PMID19618341">Transmissible mink encephalopathy - review of the etiology of a rare prion disease. Folia Neuropathol 47(2):195-204 (2009) PMID 19618341 </ref><ref name="PMID19618336">Cannibalism, kuru and anthropology. Folia Neuropathol 47(2):138-44 (2009) PMID 19618336 </ref><ref name="PMID19618335">Kuru and D. Carleton Gajdusek: a close encounter. Folia Neuropathol 47(2):114-37 (2009) PMID 19618335 </ref><ref name="PMID19618334">Thoughts on mammalian prion strains. Folia Neuropathol 47(2):104-13 (2009) PMID 19618334 </ref><ref name="PMID19618333">Reflections on a half-century in the field of transmissible spongiform encephalopathy. Folia Neuropathol 47(2):95-103 (2009) PMID 19618333 </ref><ref name="PMID18587704">Prion diseases: a riddle wrapped in a mystery inside an enigma. Folia Neuropathol 46(2):93-116 (2008) PMID 18587704 </ref><ref name="PMID18368623">Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). Folia Neuropathol 46(1):1-25 (2008) PMID 18368623 </ref><ref name="PMID16823692">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 2. Folia Neuropathol 44(2):102-10 (2006) PMID 16823692 </ref><ref name="PMID16823691">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 1. Folia Neuropathol 44(2):93-101 (2006) PMID 16823691 </ref><ref name="PMID16416388">Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. Folia Neuropathol 43(4):229-43 (2005) PMID 16416388 </ref><ref name="PMID15037545">Prions: proteins as genes and infectious entities. Genes Dev 18(5):470-85 (2004) PMID 15037545 </ref><ref name="PMID16420684">Unraveling prion structures and biological functions. Genome Biol 6(13):366 (2005) PMID 16420684 </ref><ref name="PMID15820951">Prions and the blood and immune systems. Haematologica 90(4):542-8 (2005) PMID 15820951 </ref><ref name="PMID9300662">Human prion diseases and bovine spongiform encephalopathy (BSE). Hum Mol Genet 6(10):1699-705 (1997) PMID 9300662 </ref><ref name="PMID7642588">Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem 270(33):19197-200 (1995) PMID 7642588 </ref><ref name="PMID828205">Scrapie: a review of its relation to human disease and ageing. J Med Genet 13(6):479-95 (1976) PMID 828205 </ref><ref name="PMID15965195">Molecular neurology of prion disease. J Neurol Neurosurg Psychiatry 76(7):906-19 (2005) PMID 15965195 </ref><ref name="PMID14978149">Prion diseases. J Neurol Neurosurg Psychiatry 75 Suppl 1():i36-42 (2004) PMID 14978149 </ref><ref name="PMID1955893">The spongiform encephalopathies. J Neurol Neurosurg Psychiatry 54(9):761-3 (1991) PMID 1955893 </ref><ref name="PMID11724914">The molecular pathology of CJD: old and new variants. Mol Pathol 54(6):393-9 (2001) PMID 11724914 </ref><ref name="PMID9373595">Creutzfeldt-Jakob disease in the elderly. Postgrad Med J 73(863):557-9 (1997) PMID 9373595 </ref><ref name="PMID223140">Slow viruses and chronic disease of the central nervous system. Postgrad Med J 55(640):143-9 (1979) PMID 223140 </ref><ref name="PMID103082">Creutzfeldt--Jakob disease. Postgrad Med J 54(635):591-4 (1978) PMID 103082 </ref><ref name="PMID19242120">Prions in the environment: occurrence, fate and mitigation. Prion 2(4):162-9 (2008) PMID 19242120 </ref><ref name="PMID19172115">An emerging concept of prion infections as a form of transmissible cerebral amyloidosis. Prion 1(4):223-7 (2007) PMID 19172115 </ref><ref name="PMID19172114">Biological roles of prion domains. Prion 1(4):228-35 (2007) PMID 19172114 </ref><ref name="PMID19164911">A structural overview of the vertebrate prion proteins. Prion 1(3):185-97 (2007) PMID 19164911 </ref><ref name="PMID19164897">Prion stability. Prion 1(3):170-8 (2007) PMID 19164897 </ref><ref name="PMID19164893">Prion-prion interactions. Prion 1(3):161-9 (2007) PMID 19164893 </ref><ref name="PMID19164928">Yeast prions: evolution of the prion concept. Prion 1(2):94-100 (2007) PMID 19164928 </ref><ref name="PMID19164891">Prions and related phenomena. Prion 1(2):81-2 (2007) PMID 19164891 </ref><ref name="PMID19164923">Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. Prion 1(1):48-52 (2007) PMID 19164923 </ref><ref name="PMID9811807">Prions. Proc Natl Acad Sci U S A 95(23):13363-83 (1998) PMID 9811807 </ref><ref name="PMID8197105">Inherited prion diseases. Proc Natl Acad Sci U S A 91(11):4611-4 (1994) PMID 8197105 </ref><ref name="PMID7975565">Neurodegeneration in humans caused by prions. West J Med 161(3):264-72 (1994) PMID 7975565 </ref><ref name="PMID3284206">Creutzfeldt-Jakob disease, 1988. West J Med 148(3):328-9 (1988) PMID 3284206 </ref><ref name="PMID14744440">Mammalian prion biology: one century of evolving concepts. Cell 116(2):313-27 (2004) PMID 14744440 </ref><ref name="PMID9590169">Prion protein biology. Cell 93(3):337-48 (1998) PMID 9590169 </ref><ref name="PMID10801430">Prions: Portable prion domains. Curr Biol 10(9):R335-7 (2000) PMID 10801430 </ref><ref name="PMID11832240">The utility of prions. Dev Cell 2(2):143-51 (2002) PMID 11832240 </ref><ref name="PMID12354606">Prion diseases: pathogenesis and public health concerns. FEBS Lett 529(1):17-21 (2002) PMID 12354606 </ref><ref name="PMID11852045">Cellular prion protein: on the road for functions. FEBS Lett 512(1-3):25-8 (2002) PMID 11852045 </ref><ref name="PMID8682199">The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies. FEBS Lett 389(1):3-11 (1996) PMID 8682199 </ref><ref name="PMID10545332">Prion protein interconversions and the transmissible spongiform encephalopathies. Structure 7(10):R231-40 (1999) PMID 10545332 </ref>
 == Bibliographie ==
 <references />
-{{LinkWP_Miniartikel|Txt=Prion|Link=Prion}}
+{{PPA-Kupfer}}

Ossip Groth am 16. April 2010 um 16:36 Uhr

2010-04-16T16:36:57Z

← Nächstältere Version		Version vom 16. April 2010, 16:36 Uhr
Zeile 2:		Zeile 2:
	{\| class="wikitable" \|		{\| class="wikitable" \|
	\| bgcolor="#dfdfdf" \| '''Freie Übersichtsartikel'''		\| bgcolor="#dfdfdf" \| '''Freie Übersichtsartikel'''
	\| align="left" width="800" \| <ref name="PMID18391177">Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">~~. et al.,~~ Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref><ref name="PMID18245809">Prion diseases: from protein to cell pathology. Am J Pathol 172(3):555-65 (2008) PMID 18245809 </ref><ref name="PMID7717447">Etiology and pathogenesis of prion diseases. Am J Pathol 146(4):785-811 (1995) PMID 7717447 </ref><ref name="PMID4626566">Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. Am J Pathol 68(3):626-52 (1972) PMID 4626566 </ref><ref name="PMID16606761">Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63(4):497-501 (2006) PMID 16606761 </ref><ref name="PMID15824251">Human prion diseases: molecular and clinical aspects. Arch Neurol 62(4):545-52 (2005) PMID 15824251 </ref><ref name="PMID10190828">Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 56(3):357-62 (1999) PMID 10190828 </ref><ref name="PMID15154834">Prions in control of cell glycosylation. Biochem J 380(Pt 2):e5-6 (2004) PMID 15154834 </ref><ref name="PMID1968741">Prion liposomes. Biochem J 266(1):1-14 (1990) PMID 1968741 </ref><ref name="PMID16923955">Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 129(Pt 9):2297-317 (2006) PMID 16923955 </ref><ref name="PMID16816391">A systematic review of prion therapeutics in experimental models. Brain 129(Pt 9):2241-65 (2006) PMID 16816391 </ref><ref name="PMID10581227">How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 122 ( Pt 12)():2345-51 (1999) PMID 10581227 </ref><ref name="PMID11279534">Pathogenesis of prion diseases: a progress report. Cell Death Differ 7(10):889-902 (2000) PMID 11279534 </ref><ref name="PMID16391566">Prion disease genetics. Eur J Hum Genet 14(3):273-81 (2006) PMID 16391566 </ref><ref name="PMID11788778">A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. Exp Biol Med (Maywood) 227(1):4-19 (2002) PMID 11788778 </ref><ref name="PMID11444100">Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. Exp Biol Med (Maywood) 226(7):640-52 (2001) PMID 11444100 </ref><ref name="PMID11444099">A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to "new variant" CJD and bovine spongiform encephalopathy. Exp Biol Med (Maywood) 226(7):629-39 (2001) PMID 11444099 </ref><ref name="PMID19618341">Transmissible mink encephalopathy - review of the etiology of a rare prion disease. Folia Neuropathol 47(2):195-204 (2009) PMID 19618341 </ref><ref name="PMID19618336">Cannibalism, kuru and anthropology. Folia Neuropathol 47(2):138-44 (2009) PMID 19618336 </ref><ref name="PMID19618335">Kuru and D. Carleton Gajdusek: a close encounter. Folia Neuropathol 47(2):114-37 (2009) PMID 19618335 </ref><ref name="PMID19618334">Thoughts on mammalian prion strains. Folia Neuropathol 47(2):104-13 (2009) PMID 19618334 </ref><ref name="PMID19618333">Reflections on a half-century in the field of transmissible spongiform encephalopathy. Folia Neuropathol 47(2):95-103 (2009) PMID 19618333 </ref><ref name="PMID18587704">Prion diseases: a riddle wrapped in a mystery inside an enigma. Folia Neuropathol 46(2):93-116 (2008) PMID 18587704 </ref><ref name="PMID18368623">Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). Folia Neuropathol 46(1):1-25 (2008) PMID 18368623 </ref><ref name="PMID16823692">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 2. Folia Neuropathol 44(2):102-10 (2006) PMID 16823692 </ref><ref name="PMID16823691">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 1. Folia Neuropathol 44(2):93-101 (2006) PMID 16823691 </ref><ref name="PMID16416388">Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. Folia Neuropathol 43(4):229-43 (2005) PMID 16416388 </ref><ref name="PMID15037545">Prions: proteins as genes and infectious entities. Genes Dev 18(5):470-85 (2004) PMID 15037545 </ref><ref name="PMID16420684">Unraveling prion structures and biological functions. Genome Biol 6(13):366 (2005) PMID 16420684 </ref><ref name="PMID15820951">Prions and the blood and immune systems. Haematologica 90(4):542-8 (2005) PMID 15820951 </ref><ref name="PMID9300662">Human prion diseases and bovine spongiform encephalopathy (BSE). Hum Mol Genet 6(10):1699-705 (1997) PMID 9300662 </ref><ref name="PMID7642588">Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem 270(33):19197-200 (1995) PMID 7642588 </ref><ref name="PMID828205">Scrapie: a review of its relation to human disease and ageing. J Med Genet 13(6):479-95 (1976) PMID 828205 </ref><ref name="PMID15965195">Molecular neurology of prion disease. J Neurol Neurosurg Psychiatry 76(7):906-19 (2005) PMID 15965195 </ref><ref name="PMID14978149">Prion diseases. J Neurol Neurosurg Psychiatry 75 Suppl 1():i36-42 (2004) PMID 14978149 </ref><ref name="PMID1955893">The spongiform encephalopathies. J Neurol Neurosurg Psychiatry 54(9):761-3 (1991) PMID 1955893 </ref><ref name="PMID11724914">The molecular pathology of CJD: old and new variants. Mol Pathol 54(6):393-9 (2001) PMID 11724914 </ref><ref name="PMID9373595">Creutzfeldt-Jakob disease in the elderly. Postgrad Med J 73(863):557-9 (1997) PMID 9373595 </ref><ref name="PMID223140">Slow viruses and chronic disease of the central nervous system. Postgrad Med J 55(640):143-9 (1979) PMID 223140 </ref><ref name="PMID103082">Creutzfeldt--Jakob disease. Postgrad Med J 54(635):591-4 (1978) PMID 103082 </ref><ref name="PMID19242120">Prions in the environment: occurrence, fate and mitigation. Prion 2(4):162-9 (2008) PMID 19242120 </ref><ref name="PMID19172115">An emerging concept of prion infections as a form of transmissible cerebral amyloidosis. Prion 1(4):223-7 (2007) PMID 19172115 </ref><ref name="PMID19172114">Biological roles of prion domains. Prion 1(4):228-35 (2007) PMID 19172114 </ref><ref name="PMID19164911">A structural overview of the vertebrate prion proteins. Prion 1(3):185-97 (2007) PMID 19164911 </ref><ref name="PMID19164897">Prion stability. Prion 1(3):170-8 (2007) PMID 19164897 </ref><ref name="PMID19164893">Prion-prion interactions. Prion 1(3):161-9 (2007) PMID 19164893 </ref><ref name="PMID19164928">Yeast prions: evolution of the prion concept. Prion 1(2):94-100 (2007) PMID 19164928 </ref><ref name="PMID19164891">Prions and related phenomena. Prion 1(2):81-2 (2007) PMID 19164891 </ref><ref name="PMID19164923">Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. Prion 1(1):48-52 (2007) PMID 19164923 </ref><ref name="PMID9811807">Prions. Proc Natl Acad Sci U S A 95(23):13363-83 (1998) PMID 9811807 </ref><ref name="PMID8197105">Inherited prion diseases. Proc Natl Acad Sci U S A 91(11):4611-4 (1994) PMID 8197105 </ref><ref name="PMID7975565">Neurodegeneration in humans caused by prions. West J Med 161(3):264-72 (1994) PMID 7975565 </ref><ref name="PMID3284206">Creutzfeldt-Jakob disease, 1988. West J Med 148(3):328-9 (1988) PMID 3284206 </ref><ref name="PMID14744440">Mammalian prion biology: one century of evolving concepts. Cell 116(2):313-27 (2004) PMID 14744440 </ref><ref name="PMID9590169">Prion protein biology. Cell 93(3):337-48 (1998) PMID 9590169 </ref><ref name="PMID10801430">Prions: Portable prion domains. Curr Biol 10(9):R335-7 (2000) PMID 10801430 </ref><ref name="PMID11832240">The utility of prions. Dev Cell 2(2):143-51 (2002) PMID 11832240 </ref><ref name="PMID12354606">Prion diseases: pathogenesis and public health concerns. FEBS Lett 529(1):17-21 (2002) PMID 12354606 </ref><ref name="PMID11852045">Cellular prion protein: on the road for functions. FEBS Lett 512(1-3):25-8 (2002) PMID 11852045 </ref><ref name="PMID8682199">The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies. FEBS Lett 389(1):3-11 (1996) PMID 8682199 </ref><ref name="PMID10545332">Prion protein interconversions and the transmissible spongiform encephalopathies. Structure 7(10):R231-40 (1999) PMID 10545332 </ref>		\| align="left" width="800" \| <ref name="PMID18391177">Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref><ref name="PMID18245809">Prion diseases: from protein to cell pathology. Am J Pathol 172(3):555-65 (2008) PMID 18245809 </ref><ref name="PMID7717447">Etiology and pathogenesis of prion diseases. Am J Pathol 146(4):785-811 (1995) PMID 7717447 </ref><ref name="PMID4626566">Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. Am J Pathol 68(3):626-52 (1972) PMID 4626566 </ref><ref name="PMID16606761">Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63(4):497-501 (2006) PMID 16606761 </ref><ref name="PMID15824251">Human prion diseases: molecular and clinical aspects. Arch Neurol 62(4):545-52 (2005) PMID 15824251 </ref><ref name="PMID10190828">Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 56(3):357-62 (1999) PMID 10190828 </ref><ref name="PMID15154834">Prions in control of cell glycosylation. Biochem J 380(Pt 2):e5-6 (2004) PMID 15154834 </ref><ref name="PMID1968741">Prion liposomes. Biochem J 266(1):1-14 (1990) PMID 1968741 </ref><ref name="PMID16923955">Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 129(Pt 9):2297-317 (2006) PMID 16923955 </ref><ref name="PMID16816391">A systematic review of prion therapeutics in experimental models. Brain 129(Pt 9):2241-65 (2006) PMID 16816391 </ref><ref name="PMID10581227">How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 122 ( Pt 12)():2345-51 (1999) PMID 10581227 </ref><ref name="PMID11279534">Pathogenesis of prion diseases: a progress report. Cell Death Differ 7(10):889-902 (2000) PMID 11279534 </ref><ref name="PMID16391566">Prion disease genetics. Eur J Hum Genet 14(3):273-81 (2006) PMID 16391566 </ref><ref name="PMID11788778">A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. Exp Biol Med (Maywood) 227(1):4-19 (2002) PMID 11788778 </ref><ref name="PMID11444100">Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. Exp Biol Med (Maywood) 226(7):640-52 (2001) PMID 11444100 </ref><ref name="PMID11444099">A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to "new variant" CJD and bovine spongiform encephalopathy. Exp Biol Med (Maywood) 226(7):629-39 (2001) PMID 11444099 </ref><ref name="PMID19618341">Transmissible mink encephalopathy - review of the etiology of a rare prion disease. Folia Neuropathol 47(2):195-204 (2009) PMID 19618341 </ref><ref name="PMID19618336">Cannibalism, kuru and anthropology. Folia Neuropathol 47(2):138-44 (2009) PMID 19618336 </ref><ref name="PMID19618335">Kuru and D. Carleton Gajdusek: a close encounter. Folia Neuropathol 47(2):114-37 (2009) PMID 19618335 </ref><ref name="PMID19618334">Thoughts on mammalian prion strains. Folia Neuropathol 47(2):104-13 (2009) PMID 19618334 </ref><ref name="PMID19618333">Reflections on a half-century in the field of transmissible spongiform encephalopathy. Folia Neuropathol 47(2):95-103 (2009) PMID 19618333 </ref><ref name="PMID18587704">Prion diseases: a riddle wrapped in a mystery inside an enigma. Folia Neuropathol 46(2):93-116 (2008) PMID 18587704 </ref><ref name="PMID18368623">Cell death and autophagy in prion diseases (transmissible spongiform encephalopathies). Folia Neuropathol 46(1):1-25 (2008) PMID 18368623 </ref><ref name="PMID16823692">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 2. Folia Neuropathol 44(2):102-10 (2006) PMID 16823692 </ref><ref name="PMID16823691">Variant CJD (vCJD) and bovine spongiform encephalopathy (BSE): 10 and 20 years on: part 1. Folia Neuropathol 44(2):93-101 (2006) PMID 16823691 </ref><ref name="PMID16416388">Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence. Folia Neuropathol 43(4):229-43 (2005) PMID 16416388 </ref><ref name="PMID15037545">Prions: proteins as genes and infectious entities. Genes Dev 18(5):470-85 (2004) PMID 15037545 </ref><ref name="PMID16420684">Unraveling prion structures and biological functions. Genome Biol 6(13):366 (2005) PMID 16420684 </ref><ref name="PMID15820951">Prions and the blood and immune systems. Haematologica 90(4):542-8 (2005) PMID 15820951 </ref><ref name="PMID9300662">Human prion diseases and bovine spongiform encephalopathy (BSE). Hum Mol Genet 6(10):1699-705 (1997) PMID 9300662 </ref><ref name="PMID7642588">Prion protein isoforms, a convergence of biological and structural investigations. J Biol Chem 270(33):19197-200 (1995) PMID 7642588 </ref><ref name="PMID828205">Scrapie: a review of its relation to human disease and ageing. J Med Genet 13(6):479-95 (1976) PMID 828205 </ref><ref name="PMID15965195">Molecular neurology of prion disease. J Neurol Neurosurg Psychiatry 76(7):906-19 (2005) PMID 15965195 </ref><ref name="PMID14978149">Prion diseases. J Neurol Neurosurg Psychiatry 75 Suppl 1():i36-42 (2004) PMID 14978149 </ref><ref name="PMID1955893">The spongiform encephalopathies. J Neurol Neurosurg Psychiatry 54(9):761-3 (1991) PMID 1955893 </ref><ref name="PMID11724914">The molecular pathology of CJD: old and new variants. Mol Pathol 54(6):393-9 (2001) PMID 11724914 </ref><ref name="PMID9373595">Creutzfeldt-Jakob disease in the elderly. Postgrad Med J 73(863):557-9 (1997) PMID 9373595 </ref><ref name="PMID223140">Slow viruses and chronic disease of the central nervous system. Postgrad Med J 55(640):143-9 (1979) PMID 223140 </ref><ref name="PMID103082">Creutzfeldt--Jakob disease. Postgrad Med J 54(635):591-4 (1978) PMID 103082 </ref><ref name="PMID19242120">Prions in the environment: occurrence, fate and mitigation. Prion 2(4):162-9 (2008) PMID 19242120 </ref><ref name="PMID19172115">An emerging concept of prion infections as a form of transmissible cerebral amyloidosis. Prion 1(4):223-7 (2007) PMID 19172115 </ref><ref name="PMID19172114">Biological roles of prion domains. Prion 1(4):228-35 (2007) PMID 19172114 </ref><ref name="PMID19164911">A structural overview of the vertebrate prion proteins. Prion 1(3):185-97 (2007) PMID 19164911 </ref><ref name="PMID19164897">Prion stability. Prion 1(3):170-8 (2007) PMID 19164897 </ref><ref name="PMID19164893">Prion-prion interactions. Prion 1(3):161-9 (2007) PMID 19164893 </ref><ref name="PMID19164928">Yeast prions: evolution of the prion concept. Prion 1(2):94-100 (2007) PMID 19164928 </ref><ref name="PMID19164891">Prions and related phenomena. Prion 1(2):81-2 (2007) PMID 19164891 </ref><ref name="PMID19164923">Antiprion drugs as chemical tools to uncover mechanisms of prion propagation. Prion 1(1):48-52 (2007) PMID 19164923 </ref><ref name="PMID9811807">Prions. Proc Natl Acad Sci U S A 95(23):13363-83 (1998) PMID 9811807 </ref><ref name="PMID8197105">Inherited prion diseases. Proc Natl Acad Sci U S A 91(11):4611-4 (1994) PMID 8197105 </ref><ref name="PMID7975565">Neurodegeneration in humans caused by prions. West J Med 161(3):264-72 (1994) PMID 7975565 </ref><ref name="PMID3284206">Creutzfeldt-Jakob disease, 1988. West J Med 148(3):328-9 (1988) PMID 3284206 </ref><ref name="PMID14744440">Mammalian prion biology: one century of evolving concepts. Cell 116(2):313-27 (2004) PMID 14744440 </ref><ref name="PMID9590169">Prion protein biology. Cell 93(3):337-48 (1998) PMID 9590169 </ref><ref name="PMID10801430">Prions: Portable prion domains. Curr Biol 10(9):R335-7 (2000) PMID 10801430 </ref><ref name="PMID11832240">The utility of prions. Dev Cell 2(2):143-51 (2002) PMID 11832240 </ref><ref name="PMID12354606">Prion diseases: pathogenesis and public health concerns. FEBS Lett 529(1):17-21 (2002) PMID 12354606 </ref><ref name="PMID11852045">Cellular prion protein: on the road for functions. FEBS Lett 512(1-3):25-8 (2002) PMID 11852045 </ref><ref name="PMID8682199">The Ninth Datta Lecture. Molecular biology of transmissible spongiform encephalopathies. FEBS Lett 389(1):3-11 (1996) PMID 8682199 </ref><ref name="PMID10545332">Prion protein interconversions and the transmissible spongiform encephalopathies. Structure 7(10):R231-40 (1999) PMID 10545332 </ref>

Ossip Groth am 15. April 2010 um 15:07 Uhr

2010-04-15T15:07:30Z

← Nächstältere Version		Version vom 15. April 2010, 15:07 Uhr
Zeile 2:		Zeile 2:
	{\| class="wikitable" \|		{\| class="wikitable" \|
	\| bgcolor="#dfdfdf" \| '''Freie Übersichtsartikel'''		\| bgcolor="#dfdfdf" \| '''Freie Übersichtsartikel'''
	\| align="left" width="800" \| <ref name="PMID18391177">~~. et al.,~~ Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">. et al., Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref>		\| align="left" width="800" \| <ref name="PMID18391177">Physiology of the prion protein. Physiol Rev 88(2):673-728 (2008) PMID 18391177 </ref><ref name="PMID1916104">. et al., Prions and prion proteins. FASEB J 5(13):2799-807 (1991) PMID 1916104 </ref><ref name="PMID18245809">Prion diseases: from protein to cell pathology. Am J Pathol 172(3):555-65 (2008) PMID 18245809 </ref><ref name="PMID7717447">Etiology and pathogenesis of prion diseases. Am J Pathol 146(4):785-811 (1995) PMID 7717447 </ref><ref name="PMID4626566">Subacute spongiform virus encephalopathies. Scrapie, Kuru and Creutzfeldt-Jakob disease: a review. Am J Pathol 68(3):626-52 (1972) PMID 4626566 </ref><ref name="PMID16606761">Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 63(4):497-501 (2006) PMID 16606761 </ref><ref name="PMID15824251">Human prion diseases: molecular and clinical aspects. Arch Neurol 62(4):545-52 (2005) PMID 15824251 </ref><ref name="PMID10190828">Creutzfeldt-Jakob disease with florid-type plaques after cadaveric dura mater grafting. Arch Neurol 56(3):357-62 (1999) PMID 10190828 </ref><ref name="PMID15154834">Prions in control of cell glycosylation. Biochem J 380(Pt 2):e5-6 (2004) PMID 15154834 </ref><ref name="PMID1968741">Prion liposomes. Biochem J 266(1):1-14 (1990) PMID 1968741 </ref><ref name="PMID16923955">Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity. Brain 129(Pt 9):2297-317 (2006) PMID 16923955 </ref><ref name="PMID16816391">A systematic review of prion therapeutics in experimental models. Brain 129(Pt 9):2241-65 (2006) PMID 16816391 </ref><ref name="PMID10581227">How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 122 ( Pt 12)():2345-51 (1999) PMID 10581227 </ref><ref name="PMID11279534">Pathogenesis of prion diseases: a progress report. Cell Death Differ 7(10):889-902 (2000) PMID 11279534 </ref><ref name="PMID16391566">Prion disease genetics. Eur J Hum Genet 14(3):273-81 (2006) PMID 16391566 </ref><ref name="PMID11788778">A critical review of the nature of the spongiform encephalopathy agent: protein theory versus virus theory. Exp Biol Med (Maywood) 227(1):4-19 (2002) PMID 11788778 </ref><ref name="PMID11444100">Lingering doubts about spongiform encephalopathy and Creutzfeldt-Jakob disease. Exp Biol Med (Maywood) 226(7):640-52 (2001) PMID 11444100 </ref><ref name="PMID11444099">A critical review of atypical cerebellum-type Creutzfeldt-Jakob disease: its relationship to "new variant" CJD and bovine spongiform encephalopathy. Exp Biol Med (Maywood) 226(7):629-39 (2001) PMID 11444099 </ref><ref name="PMID19618341">Transmissible mink encephalopathy - review of the etiology of a rare prion disease. Folia Neuropathol 47(2):195-204 (2009) PMID 19618341 </ref><ref name="PMID19618336">Cannibalism, kuru and anthropology. Folia Neuropathol 47(2):138-44 (2009) PMID 19618336 </ref><ref name="PMID19618335">Kuru and D. Carleton Gajdusek: a close encounter. Folia Neuropathol 47(2):114-37 (2009) PMID 19618335 </ref><ref name="PMID19618334">Thoughts on mammalian prion strains. Folia Neuropathol 47(2):104-13 (2009) PMID 19618334 </ref><ref name="PMID19618333">Reflections on a half-century in the field of transmissible spongiform encephalopathy. Folia Neuropathol 47(2):95-103 (2009) PMID 19618333 </ref><ref name="PMID18587704">Prion diseases: a riddle wrapped in a mystery inside an enigma. 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Anthoney: Vorlage

2010-03-08T22:25:59Z

Vorlage

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Ossip Groth am 9. Januar 2010 um 11:12 Uhr

2010-01-09T11:12:04Z

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== Bibliographie ==
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